Researchers analyze factors contributing to high levels of esophageal cancer in Tanzania

Dec. 7, 2022
3D illustration showing malignant tumor in the human esophagus

Cancer in Tanzania is an increasing health problem, particularly esophageal cancer, which represents the third most common cancer in men and the fourth most common cancer in women.

In a new study published in the Journal of Cancer Epidemiology, Associate Professor Ghada Soliman and colleagues investigated the link between poverty, access to care, health disparity and distance to a health center and survival from esophageal cancer.

Using data on esophageal cancer patients from the Ocean Road Cancer Institute (ORCI), the only national cancer hospital in Tanzania, the research team utilized datasets of all esophageal cancer patients seen at the ORCI from 2006 through 2016 to explore the role of geographic residence of patients and possible regional risk factors. The team also investigated whether the distance from the patient’s places of residence was related to delayed treatment of advanced-stage esophageal cancer patients.

The study revealed that understanding geographic differences in epidemiologic, nutritional, and demographic factors as well as distance to treatment facilities are important factors in influencing esophageal cancer risk and outcomes in this population.

“Esophageal cancer represents a dire health problem because it often presents at an advanced stage at diagnosis and limited effective treatment options are available,” Dr. Soliman explains. “Remote areas of Tanzania may not be served by a regional hospital that can provide diagnostic laboratory services and radiology. Many remote areas also lack the endoscopic equipment and personnel that would allow for greater detection of esophageal cancer.”

Increasing the capacity of referral hospitals to offer more advanced diagnostic laboratory and radiology services and providing greater endoscopic equipment and training can lead to earlier detection of esophageal cancer, the researchers say.

Watkins R, Soliman GA, Mwaiselage J, Kahesa C, Msami K, Wilson ML. Distance to Health Care Facilities, Lifestyle Risk Factors, and Stage at Diagnosis in relation to Geographic Pattern of Esophageal Cancer in Tanzania, 2006-2016. J Cancer Epidemiol. 2022 Aug 22;2022:7873588. doi: 10.1155/2022/7873588. PMID: 36046119; PMCID: PMC9423990.

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